Product name: Epichlorohydrin; EPI; ECH
Alias: Epichlorohydrin, 3-chloro-1,2-epoxypropane
Chemical formula: C₃H₅ClO
Molecular weight: 92.52
CAS No.: 106-89-8
EINECS No.: 203-439- 8
UN Dangerous Goods Number: 2023
Melting point: -25.6 ℃
Boiling point: 116.11 ℃ (101.3 kPa)
Water solubility: 6.58% (wt)
Density: 1.18 g/cm³
Appearance: colorless liquid, with chloroform-like odor
Flash point; 40.6 ℃
Epichlorohydrin is a basic organic chemical raw material with a wide range of uses. It is an intermediate for synthesizing glycerin and a main raw material for synthesizing epoxy resin, chlorohydrin rubber and other products. It can be used in the manufacture of glass fiber reinforced plastics, adhesives, cation exchange resins, electrical insulation products, as well as solvents, plasticizers, stabilizers, surfactants, and pharmaceutical industries, as well as in the manufacture of various synthetic resins with special functions.
Pharmaceutical synthesis:
4-hydroxyindole and Epichlorohydrin react in ethanol solution of sodium hydroxide to form the intermediate 1-(1H-indole-4-oxy)-3-chloro-2-propanol, and then the intermediate reacts with isopropylamine, The target product pindolol {1-(1H-indol-4-oxy)-3-[(1-methylethyl)amino]-2-propanol} was synthesized. Pindolol is a β-blocker discovered to enhance antidepressant effects, and can also act as a partial agonist and antagonist of 5-HT1A receptors. In addition, pindolol series of drugs can also be used to treat many reasons It has a significant effect on vasovagal syncope.
Production of glycerol:
Four-step synthesis with Epichlorohydrin as raw material, mature technology, low unit consumption, product purity ≥ 99%, the production capacity of the pressurized method is 7.5 times higher than that of the normal pressure method, and the yield is 98%, but the process is long, and the consumption of chlorine and Alkali is high, calcium chloride and organic chloride are seriously corroded in production, and the amount of sewage is large. France changed to direct hydrolysis (without Epichlorohydrin), without lime milk, without calcium chloride post-treatment.
Preparation of epoxy resin:
Bisphenol A epoxy resin has good insulating properties, adhesion ability, high temperature resistance, outstanding mechanical properties, etc. It can be used for indoor and outdoor painting, casting of electronic products and chemical equipment, etc. The general synthesis method is mainly that bisphenol A and Epichlorohydrin undergo ring-opening and ring-closing reactions in sodium hydroxide aqueous solution to obtain epoxy resin. The synthesis of bisphenol A epoxy resin mainly includes one-step and two-step processes. The one-step synthesis reaction is carried out in sodium hydroxide or potassium hydroxide solution, but Epichlorohydrin is often hydrolyzed in strong alkaline aqueous solution, resulting in low epoxy value and high chlorine content of the product. The two-step synthesis reaction process is long, and the raw material consumption and purification process are troublesome. There are also researchers in the industry who have developed the use of solid alkali method and solvent method.
Surfactant:
Using dimethylamine, tertiary amine and Epichlorohydrin as raw materials, and polyethylene polyamine as cross-linking agent, an Epichlorohydrin amine clear water agent can be synthesized. This clear water agent has excellent oil removal and suspended solid removal performance.
Under the catalysis of tetrabutylammonium bromide, the demulsifier DLA-6-1 was synthesized by ring-opening polymerization with phenolic aldehyde resin polyether demulsifier DLA-6 and Epichlorohydrin, which was used as a demulsifier for ASP flooding produced fluid. .
EP Thinner:
Epoxy resin has high viscosity, which is very inconvenient for practical operation (especially casting process and impregnation process), and the cured resin is brittle, which limits its application. An easy way to eliminate the above drawbacks is to use thinners. Commonly used diluents are acetone, benzene, toluene, phthalates, etc. These diluents do not participate in the chemical reaction in the resin curing process. Therefore, when the resin is cured, some of them will escape, resulting in defects such as air bubbles, volume shrinkage and internal stress, which affect the quality of epoxy resin products. A new type of reactive diluent, such as phenolic glycidyl ether, was synthesized by using phenol and Epichlorohydrin as raw materials. The long bond substituent in the molecule of this reactive diluent not only participates in the curing reaction of the resin, but also It can play a good role in softening, so compared with commonly used reactive diluents such as propylene oxide phenyl ether (690 for short), the flexibility is more prominent, which can effectively reduce the viscosity of epoxy resin and improve the performance of epoxy resin products. Flexible and imparts excellent mechanical and insulating properties.
Preparation of chlorohydrin rubber: Chlorohydrin rubber
produced with Epichlorohydrin as raw material is a new variety of rubber. Chlorohydrin rubber is a rubber with chlorine in the side groups and ether bonds in the main chain. It is made of Epichlorohydrin, ethylene oxide and allyl condense Glyceryl ether is an elastomer formed by homopolymerization or copolymerization of three monomers, so it can be divided into ECH homopolymer, ECH/EO binary copolymer and ECH/EO/AGE terpolymer. The structure of chloroether rubber determines that it has many special properties. Copolymerized chloroether rubber is not easy to swell in common oil and common solvents, has good heat resistance, oil resistance, weather resistance and air tightness, and has greater flexibility at low temperature without plasticizers. Some unique features of butyl and butyl rubber. It has attracted much attention because of its unique semi-conductive properties, which are used in the conductive rubber rollers and developing rubber rollers of equipment such as copiers and laser printers.
Paper Enhancer:
PAE resin is the most widely used wetting strength agent today and is a synthetic product of adipic acid, diethylenetriamine and Epichlorohydrin. The principle of action of PAE resin is to form a network water-resistant structure. Fischer et al. pointed out that the mechanism of PAE resin humidification strength is not generated by the bridging of resin and cellulose, but by the bridge between PAE resins to form a water-resistant structure.
Packaging and storage:
1. Store in a cool, ventilated place 's warehouse. Keep away from fire and heat sources. The storage temperature should not exceed 30℃. It should be stored separately from acids, alkalis, and edible chemicals, and should not be mixed. Use explosion-proof lighting and ventilation facilities. Prohibit the use of mechanical equipment and tools that are prone to sparks. Storage areas should be equipped with emergency release equipment and suitable containment materials.
2. Since ferric chloride or tin chloride can promote the self-polymerization reaction of Epichlorohydrin, it should be stored in dry and clean galvanized iron drums, 200kg per drum. Store in a cool, ventilated and dry place, away from fire and heat sources. Storage and transportation according to the regulations of flammable and toxic substances.